Fragment Screening by Native State Mass Spectrometry
نویسندگان
چکیده
منابع مشابه
Native Mass Spectrometry in Fragment-Based Drug Discovery.
The advent of native mass spectrometry (MS) in 1990 led to the development of new mass spectrometry instrumentation and methodologies for the analysis of noncovalent protein-ligand complexes. Native MS has matured to become a fast, simple, highly sensitive and automatable technique with well-established utility for fragment-based drug discovery (FBDD). Native MS has the capability to directly d...
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ژورنال
عنوان ژورنال: Australian Journal of Chemistry
سال: 2013
ISSN: 0004-9425
DOI: 10.1071/ch13190